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I). Function
A). support
B). protection
C). movement
D). mineral storage
E). blood cell formation
II). Skeletal Cartilage: Hyaline Cartilage
A). articular cartilage
B). costal cartilage
C). nasal cartilage
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III). Long Bone Anatomy:
A). diaphysis
B). epiphysis
The epiphysis is usually covered in articular cartilage
C). epiphyseal line or plate:
IV). Bone Structure
A). compact bone
structural units called osteons.
Ostean consists of long cylinders that run parallel to the long axis of the bone.
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Structure of an osteon
1). lamella: concentric ring
2). haverson’s canal: runs through the core .
3). perforating canals: Connect the Haverson’s canals
4). lacuna: contain osteocytes (mature bone cells)
Types of osteocytes
i). osteoblasts: build bone
ii). osteoclasts: consume or remove bone
B). spongy bone
honeycomb or network of flat pieces filled with:
1). red bone marrow:
2). yellow bone marrow:
C). periosteum
The periosteum is supplied with nerve fibers, lymphatic vessels and blood vessels, which enter the bone.
It also contains osteoblasts (bone builders) & osteoclasts (bone breakers)
V). bone development
: Bone tissue formationA). osteogenesis
1. cell types
build calcium matrixi. oseteoblasts:
ii. osteoclasts: reabsorb calcium matrix
2. ossification: formation of bone
cartilage with bone matrixOssification Replacing
| Intramembranous Ossification occurs in flat bones only |
| Endochondral ossification occurs in long bones and all other bones |
3). Differences between Intramembranous Ossification & Endochondral Ossification
a. long bones ossify along hyaline cartilage models
b. flat bones follow membrane like layers of unspecified connective tissue.
ossify inside with spongy bone and work outward to compact bonc. flat bones
d. long bones ossify on the outside with compact bone and move inward to spongy bone.
B). Intramembranous Ossification of flat bones
1). An ossification center appears in the connective tissue.
2). A bone matrix is secreted in the fibrous membrane.
3). Woven bone and periosteum form.
4). Bone collar of compact bone forms and red bone marrow appears.
C). Endochrondral Ossification
1). Formation of hyaline cartilage model
2). A bone collar forms around the diaphysis of the hyaline cartilage
3). Cartilage in the center of the diaphysis calcifies and then cavitates
4). The periosteal bud invades the internal cavity and spongy bone forms.
The bud contains a nutrient artery and osteoclasts
5). The diaphysis elongates and a medullary cavity forms
6). The epiphysis ossify.
*Hyaline cartilage remains on the growth plate and the articulating surface.
VI). Bone Remodeling
Weekly recycle 5% to 7% of bone mass. With a replacement of spongy bone every 4 years and a replacement of compact bone every 10 years.
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osteoblasts: Bone deposit occurs at injury sites and for strengthening | |
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osteoclasts: Bone resorption |
Controlled by:
1). Negative feedback
Ca++loop that maintains blood calcium.
It involves the hormones: Parathyroid Hormone and Calcitonin.
PARATHYROID HORMONE
if blood Ca++ is low
ß
Parathyroid Hormone is released
ß
Ca++ is reabsorbed from bone by osteoclasts
CALCITONIN HORMONE
if blood Ca++ is high
ß
Calcitonin is released
ß
Ca++ is absorbed into the bone by osteoblasts
2). Mechanical & gravitational forces.
Wolf’s Law
Bone grows where stressors are placed on it.
VII). Bone Fractures
A). Classification of fractures
1). non-displaced fractures
2). displaced fractures
3). complete fracture
4). incomplete fracture
5). open (compound) fracture
6). closed (simple) fracture
7). closed reduction
8). open reduction
B). Types of fractures
1). green stick
2). partial or fissure
3). comminuted fracture
4). depressed
5). transverse fracture
6). oblique fracture
VIII). Repair of Fractures
STEP1: A hematoma forms over the fracture site.
STEP2: Fibrocartilaginous callus formation.
STEP3: Bony callus formation
STEP4: Bone remodeling
Mnemonic
Go C3PO
(use 3 Cs)
Greenstick
Open
Complete
ClosedComminuted
Partial
Other
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